Similar from what was shown with activins, we showed that Cripto binds TGF-1 and reduces TGF-1 crosslinking to its type We receptor, TRI [20]. co-receptor to create energetic signaling complexes with activin receptors [3,4,8,64-66]. EGF-CFC proteins are recognized to work cell autonomously as anchored cell surface area co-receptors however they … Continue reading Similar from what was shown with activins, we showed that Cripto binds TGF-1 and reduces TGF-1 crosslinking to its type We receptor, TRI [20]